Predicted values for lung diffusing capacity in healthy children

Predicted values for lung diffusing capacity in healthy children.

Lung diffusing capacity was measured in 92 healthy Caucasian children (52 boys and 40 girls), ranging in age from 6 to 17 years, using the single breath carbon monoxide technique (DLCO). Multiple regression equations were developed to predict the DLCO value. Standing height, gender, weight, and age were significant factors in the prediction of DLCO. Sitting height was not a significant covariat...

Normal Predicted Values of Single-Breath Diffusing Capacity of the Lung in Healthy Nonsmoking Adults

Reference values for maximal work capacity in healthy children.

Recently, the European Respiratory Journal published a paper by GULMANS et al. [1] on reference values for maximal work capacity (Wmax) in healthy children [1]. The paper described the Wmax of boys and girls using a model which related Wmax per kilogram of fat free mass (FFM) to age and gender. For the model to be valid the relationship between Wmax and FFM should have been a proportionality (i...

Reference values for lung function tests. III. Carbon monoxide diffusing capacity (transfer factor).

Carbon monoxide diffusing capacity (DLCO) or transfer factor (TLCO) is a particularly useful test of the appropriateness of gas exchange across the lung alveolocapillary membrane. With the purpose of establishing predictive equations for DLCO using a non-smoking sample of the adult Brazilian population, we prospectively evaluated 100 subjects (50 males and 50 females aged 20 to 80 years), rando...

The influence of pulmonary vascular pressures on lung diffusing capacity during incremental exercise in healthy aging

Alveolar-capillary surface area for pulmonary gas exchange falls with aging, causing a reduction in lung diffusing capacity for carbon monoxide (DLCO). However, during exercise additional factors may influence DLCO, including pulmonary blood flow and pulmonary vascular pressures. First, we sought to determine the age-dependent effect of incremental exercise on pulmonary vascular pressures and D...